Motif ID: NANOG{mouse}.p2

Z-value: 1.104


Transcription factors associated with NANOG{mouse}.p2:

Gene SymbolEntrez IDGene Name
Nanog 71950 Nanog homeobox

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogchr6_+_1226575060.064.2e-01Click!


Activity profile for motif NANOG{mouse}.p2.

activity profile for motif NANOG{mouse}.p2


Sorted Z-values histogram for motif NANOG{mouse}.p2

Sorted Z-values for motif NANOG{mouse}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG{mouse}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_80421054 31.143 NM_016965
 Nckap1
NCK-associated protein 1
chr7_+_138079669 21.749 NM_019564
 Htra1
HtrA serine peptidase 1
chr9_-_7932402 21.411 Yap1
yes-associated protein 1
chr12_+_30687597 20.916 Pxdn
peroxidasin homolog (Drosophila)
chr1_-_194681914 17.507 NM_198247
 Sertad4
SERTA domain containing 4
chr12_+_110782654 16.828 Meg3
maternally expressed 3
chr6_+_43215604 13.651 NM_133674
 Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr15_+_78258993 12.637 NM_001081367
 Kctd17
potassium channel tetramerisation domain containing 17
chr14_+_51716032 12.131 Ang
Rnase4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family 4
chr9_-_31019412 11.827 Aplp2
amyloid beta (A4) precursor-like protein 2
chr12_+_80130149 11.815 NM_181073
 Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr16_+_62854129 11.495 NM_011173
 Pros1
protein S (alpha)
chr1_+_137635977 10.876 Csrp1
cysteine and glycine-rich protein 1
chr6_-_54543121 10.569 NM_153573
 Fkbp14
FK506 binding protein 14
chr19_-_44476302 10.404 Scd1
stearoyl-Coenzyme A desaturase 1
chr2_+_121692687 10.219 NM_177054
NM_199038
 Casc4

cancer susceptibility candidate 4

chr15_+_78858641 9.587 NM_008197
 H1f0
H1 histone family, member 0
chr2_+_121692805 9.239 Casc4
cancer susceptibility candidate 4
chr9_+_72596925 9.233 Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr14_+_30781514 9.041 NM_019979
 Selk
selenoprotein K

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
5.56 6.49e-03 GO:0006694 steroid biosynthetic process
3.57 9.56e-03 GO:0008202 steroid metabolic process
2.13 7.80e-03 GO:0006629 lipid metabolic process
1.78 9.71e-04 GO:0065008 regulation of biological quality
1.27 8.84e-03 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
2.48 3.40e-02 GO:0044297 cell body
2.48 4.90e-02 GO:0043025 neuronal cell body
2.42 4.80e-07 GO:0005626 insoluble fraction
2.39 2.03e-06 GO:0005624 membrane fraction
2.11 1.00e-05 GO:0000267 cell fraction
1.95 1.73e-03 GO:0005783 endoplasmic reticulum
1.90 2.69e-03 GO:0042995 cell projection
1.73 5.07e-03 GO:0005829 cytosol
1.68 1.38e-02 GO:0005739 mitochondrion
1.61 1.06e-12 GO:0044444 cytoplasmic part
1.46 1.30e-13 GO:0005737 cytoplasm
1.32 5.27e-08 GO:0043226 organelle
1.31 1.15e-07 GO:0043229 intracellular organelle
1.30 1.03e-10 GO:0005622 intracellular
1.29 4.58e-09 GO:0044424 intracellular part
1.28 5.97e-05 GO:0043227 membrane-bounded organelle
1.28 1.25e-04 GO:0043231 intracellular membrane-bounded organelle
1.12 4.55e-04 GO:0005623 cell
1.12 4.55e-04 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
2.15 4.04e-03 GO:0016491 oxidoreductase activity
2.09 1.61e-03 GO:0019899 enzyme binding
1.41 1.42e-05 GO:0005515 protein binding
1.30 2.72e-02 GO:0003824 catalytic activity
1.21 1.23e-04 GO:0005488 binding